Understanding how viruses interact with and proliferate within host cells, as well as how viruses evade or co-opt the functioning immune system, is of central importance for developing therapies to fight viral diseases. Using the multiparametric image-based approach enabled by Amnis imaging flow cytometry, it is possible to identify virally infected cells and measure the impact of that infection on signal transduction cascades, cell morphology and cell death.

 

  • Characterization of platelet-monocyte complexes in HIV-1-infected individuals: possible role in HIV-associated neuroinflammation.

http://www.ncbi.nlm.nih.gov/pubmed/24729609