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High Resolution Flow Microscopy – ImageStream X (ISX): Virology

Understanding how viruses interact with and proliferate within host cells, as well as how viruses evade or co-opt the functioning immune system, is of central importance for developing therapies to fight viral diseases. Using the multiparametric image-based approach enabled by Amnis imaging flow cytometry, it is possible to identify virally infected cells and measure the impact of that infection on signal transduction cascades, cell morphology and cell death.

  • Co-localization of CpGB to lysosomes and endosomes in primary plasmacytoid dendritic cells
  • HIV-specific translocation of NFAT
  • The Interplays between Autophagy and Apoptosis Induced by Enterovirus 71

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0056966

  • Contrasting Life Strategies of Viruses that Infect Photo- and Heterotrophic Bacteria, as Revealed by Viral Tagging

http://mbio.asm.org/content/3/6/e00373-12.long

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