Overview and technology
The Acuity Echo is the clinical, CE-Mark, MSOT (Multi-Spectral Optoacoustic Tomography). This system utilizes a unique handheld detector for the detection of optoacoustic signals emitted by laser excitation in the spectrum of 680-1300nm. Using a tunable laser, the MSOT acquires the acoustic signal emitted per wavelength excitation in a tomographic fashion. This allows the reconstruction of a 3D image that contains both anatomical and molecular information based on the absorbance spectrum of each material, such as tissue, oxygenated hemoglobin, deoxygenated hemoglobin, fat tissue, bone, near-infrared molecular markers (ICG), nanoparticles (GNR, GNP), and more. An image per wavelength is taken each 10th of a second enabling fast scanning of entire cross-sections for kinetics and biodistribution studies. For the anatomical image, a novel 3D ultrasound tomography is used to give an incredibly sharp image.
The Acuity Echo is frequently used for imaging tumors that are relatively superficial such as melanoma, head and neck tumors, and more.
Besides tumors, the technology is great for imaging inflammation and is the only non-invasive method for imaging IBD, Crohn’s disease, etc.
The Acuity Echo is the only system in the clinic today capable of non-invasive, non-toxic live 3D imaging of tumors and their molecular properties such as oxygenation, live vs necrotic tissue. This method is extremely useful for measuring disease and tracking therapeutics with minimal discomfort and stress for patients.