Pre-clinical Imaging

Overview

For many years in-vivo studies were conducted by sacrificing many lab animals at different time/disease points for longitudinal studies. In the past 2 decades, pre-clinical images have provided the possibility to track biological processes within the same animal over time, thus giving better insight and less variability in the studies. Today there are more in-vivo imaging modalities available for pre-clinical work than there are for clinical use, often with increased capabilities. Today pre-clinical imaging is the cornerstone of advanced and biomedical research and promotes transition to clinical studies and therapy.

Use Cases

Pre-clinical imaging is often used to track pathologies over time. The most common uses are for tumor tracking and measurement/quantification, disease progression, therapeutic agent tracking for localization, biodistribution, and pharma-kinetics.

Unique Benefits

Power your research with quality longitudinal data that is compatible with downstream clinical work.

Mediso is world leading manufacturer of clinical and pre-clinical multi modal in-vivo imaging systems that combine nuclear imaging together with MRI (3T,7T) and CT. The Nanoscan product line is leading the world of pre-clinical research with best in class resolution and sensitivity.

Fluorescence and bioluminescence is the most common method of pre-clinical in-vivo imaging. By using fluorescent or bioluminescent reporter genes it is possible to track gene expression, tissue growth, response to therapy, and much more applications.

Ultrasound works by transmitting ultrasound waves and detecting the waves that bounce back from structures live images of soft tissue, vasculature, and organs are reconstructed. By using the doppler effect it is possible to measure to direction and speed of blood flow in blood vessels and the heart. Ultrasound is preferred for many applications due to its quick, real-time imaging with no required contrast agents or radiation. The pre-clinical ultrasound systems utilize high frequency to resolve small structures in rodents, including 6.5 days-old embryos.

Pre-clinical Imaging

Mediso nanoScan PET/MRI

Fluorescence and Bioluminescence Imaging

Ultrasound Imaging